MyBioSource.com's ARHGEF9 Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, Immunohistochemistry, and Western Blot. The ARHGEF9 Polyclonal Antibody was generated using ARHGEF9, Collybistin, and HPEM-2 as the antigen and it reacts with Human, Mouse, and Rat.
Description
The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene